2025 Arizona Cardinals Fantasy Preview

2025 Arizona Cardinals Fantasy Preview Johnathan Gannon has done a good job coaching the Cardinals. In Gannon’s second season, Arizona improved to 8-9 and jumped from 24th in scoring to 12th. They also leaped to 15th in defense after ranking 31st in 2023. GM Monti Ossenfort made a concerted effort to fortify the trenches through free agency and the draft, which started with five consecutive defensive players. Don’t discount Arizona’s chances of competing in a wide-open NFC West. QB Kyler Murray had his lowest output in fantasy points per game but still finished the season as the QB10.His 0.52 EPA per dropback ranked 12th among QBs, showcasing efficiency despite inconsistent protection. He also ran for 572 yards, proving he’s back in form after the knee injury that limited him to eight games in 2023. Murray is unlikely to contend for top-5 fantasy production at the loaded QB position, but he is a good bet to post QB1 numbers at a discounted price. RB James Conner remains a reliable RB2 in fantasy, thriving in Arizona’s run-heavy scheme (11th in run plays per game). In 2024, he racked up a career-high 1,094 rushing yards, with a 2.1 yards after contact per attempt. He also chipped in 47 grabs for 414 yards and totaled nine touchdowns. Just 29, Conner led all running backs in juke rate (32.5 percent) and tackles evaded (92), showing he has plenty left in the tank. He remains a high-end RB2. Trey Benson projects as the club’s RB2 and would be a high-end handcuff for the oft-injured Conner. Fantasy managers were expecting big things from first-round WR Marvin Harrison Jr. While Harrison didn’t bust, his 62/885/8 numbers were…fine…but he was outshone by Malik Nabers. The Cardinals used Harrison downfield more than anticipated, and he ranked just 37th in target rate. The plan is to get Harrison more involved closer to the line of scrimmage in 2025. Michael Wilson and Greg Dortch return as the uninspiring supporting cast. Expect Harrison to remain blanketed by opposing defensive backs. While Arizona’s receiving corps is thin, TE Trey McBride will lead the offense in opportunities. McBride, who signed a record four-year, $76 million extension, caught 111-of-147 targets for 1,146 yards. He led all tight ends in target share (29.3 percent), route participation (86.3 percent), air yards share (25.3 percent), and EPA (19.2). McBride has become a force, with the elite fantasy production of a strong WR1 from a premium position. He’s every bit worth an early-round investment on draft day. Fantasy Grade: C QB Murray, Kyler, ARI [QB1] After missing half of the 2023 season with a knee injury, Kyler Murray rebounded nicely in 2024. He finished 10th in fantasy scoring and showed no ill effects of the injury, rushing for 572 yards (4th among QBs) and running in five scores on his own. Additionally, Murray made strides as a passer in his second season in Drew Petzing’s offense. Murray completed 68.8 percent of his attempts and ranked 5th in catchable pass rate (79.7 percent) and completion rate versus man coverage (60.7 percent). Murray delivered nine weekly QB1 finishes against only one dud game. He’s a quality target likely to be overlooked. ADVICE: Underrated QB1 with questionable weapons. RB Conner, James, ARI [RB1] James Conner is an underrated value each season, and 2025 is no different. In 2024, he posted 1,094 rushing yards, eight TDs, and 47 receptions for 414 yards (RB15 in PPR). Conner’s elite 3.7 yards after contact (1st among RBs) and 22 percent evasion rate (4th) show he still has plenty left in the tank as a dual-threat weapon. His 14.3 percent broken tackle rate showcases durability in high-volume roles (236 carries). With a $9.5M contract through 2026, Conner’s secure as the lead back, though Trey Benson may steal some touches if he can stay healthy. ADVICE: Conner remains an excellent RB2 value to target in Rounds 6-7. RB Benson, Trey, ARI [RB2] James Conner is an underrated value each season, and 2025 is no different. In 2024, he posted 1,094 rushing yards, eight TDs, and 47 receptions for 414 yards (RB15 in PPR). Conner’s elite 3.7 yards after contact (1st among RBs) and 22 percent evasion rate (4th) show he still has plenty left in the tank as a dual-threat weapon. His 14.3 percent broken tackle rate showcases durability in high-volume roles (236 carries). With a $9.5M contract through 2026, Conner’s secure as the lead back, though Trey Benson may steal some touches if he can stay healthy. ADVICE: Conner remains an excellent RB2 value to target in Rounds 6-7. WR Harrison Jr., Marvin, ARI [WR1] The hope for Marvin Harrison Jr. after a somewhat disappointing rookie season is that the Cardinals figure out how to get their prized wideout involved closer to the line of scrimmage. While that might eat into Tre McBride’s massive volume, it would fit Harrison’s skill set. Harrison ranked 6th in air yards (1,566) last season and drew 26 deep-ball targets (7th most). That resulted in poor target quality, and, inexplicably, Harrison only commanded 14 red-zone looks. Head coach Jonathan Gannon predicts Harrison will ‘take a huge jump’ in Year Two. If he does, Harrison is a screaming value. ADVICE: Muted rookie numbers versus expectations will make Harrison a strong fantasy value in Rounds 5-6. WR Wilson, Michael, ARI [WR2] ADVICE: Wilson’s sophomore numbers improved across the board, and the Cardinals didn’t make any substantial additions to threaten his WR2 role. Limited upside, but Wilson is a decent end-of-bench guy with some streaming value. WR Dortch, Greg, ARI [WR3] ADVICE: Even though he is Arizona’s third wideout, Dortch has posted back-to-back seasons with fewer than 350 receiving yards. His 4.1 ADOT last year ranked 108th and foreshadowed a role around the line of scrimmage that has little fantasy relevance. TE McBride, Trey, ARI [TE1] If you miss out on Brock Bowers, Trey McBride’s volume is an excellent consolation prize. McBride was second in targets (147) but led all tight ends with a massive
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Despite the uncertainty, Dobbs has excelled as a running quarterback, securing a rushing touchdown in four consecutive games and amassing seven games this season with at least 41 rushing yards. Facing the Broncos in Week 11, who rank fifth in fantasy points allowed to opposing quarterbacks, Dobbs should be considered a top-10 fantasy quarterback in all leagues. Sit ‘Em Trevor Lawrence (Jacksonville Jaguars) vs. Tennessee Lawrence’s fantasy performances have been inconsistent, finishing among the top-12 fantasy quarterbacks only three times this season. With a low touchdown percentage and facing a Tennessee Titans team that has allowed only 10 touchdown passes, Lawrence may struggle to deliver a strong fantasy performance. The Jaguars’ clear favoritism in the upcoming game could lead to a reliance on running back Travis Etienne Jr., further limiting Lawrence’s fantasy output. Also, if you’ve been starting Lawrence and waiting for the stats to catch up to the draft hype, this isn’t as enticing as a matchup as it appears. Baker Mayfield (Tampa Bay Buccaneers) at San Francisco Mayfield, despite recent solid fantasy performances, faces a challenging Week 11 matchup against the San Francisco 49ers. San Francisco’s defense stifled Trevor Lawrence in the previous week. And Mayfield, dealing with a thumb injury, might find it difficult against an improved 49ers pass rush featuring Chase Young. While expected to play through the injury, Mayfield is a cautious start, recommended only in Superflex and two-quarterback leagues. Running Backs Start ‘Em Darrel Henderson (Los Angeles Rams) vs. Seattle Kyren Williams’ potential return from injured reserve in Week 12 means this may be Henderson’s last shot to start. Henderson has delivered solid performances, surpassing 11 fantasy points in two of his three spot starts. Despite sharing playing time with Royce Freeman, Henderson receives valuable opportunities in the passing game and near the goal line. This week’s matchup against the Seahawks is particularly favorable, as they have allowed the fourth-most rushing yards and fifth-most rushing touchdowns to running backs since Week 6. With the Seahawks yielding a league-high 5.2 yards per carry to the position during that span, starting Henderson is recommended. Jerome Ford (Cleveland Browns) vs. Pittsburgh The last two weeks have provided stability, with both Ford and Kareem Hunt healthy. Ford, playing 64% of offensive snaps in the last two games, has run for 151 yards on 37 carries. Although Hunt dominates goal-line and short-yardage carries, limiting Ford’s touchdown potential, this week’s matchup against the Pittsburgh Steelers, allowing 4.5 yards per carry to runners this season, positions Ford as a fantasy starter. In their previous matchup against Pittsburgh, Ford ran 16 times for 106 yards and caught three passes for 25 yards and a touchdown, showcasing his ability to perform even in challenging situations. The over/under of this game indicates that running will be at a premium. Therefore, Ford looks like a good play. Sit ‘Em Najee Harris (Pittsburgh Steelers) at Cleveland Harris, while enjoying an impressive stretch over the last four weeks, faces challenges in Week 11. Jaylen Warren’s increasing share of carries and the tough matchup against the Cleveland Browns make Harris a riskier start. The Browns have the sixth-fewest fantasy points allowed to running backs this season, and Harris struggled in their Week 2 matchup. With the Steelers having the fourth-worst schedule for running backs this week, Harris may encounter difficulties in maintaining his recent fantasy success. Isiah Pacheco (Kansas City Chiefs) vs. Philadelphia Pacheco, coming off a bye week, faces a tough matchup against the Philadelphia Eagles, who rank first in fewest fantasy points allowed to opposing running backs. With Pacheco struggling in recent games and the Eagles allowing only three running backs to score at least 13.1 PPR points this season, he is a low-end starter at best for Week 11. Consider sitting Pacheco, especially considering the strength of the Eagles’ defense against running backs. Wide Receivers Start ‘Em Jayden Reed (Green Bay Packers) vs. LA Chargers Reed is emerging as the top receiver for the Packers, evidenced by his recent performance with five catches for 84 yards and a touchdown against the Steelers in Week 10. Over the past four games, Reed has achieved at least 11.1 PPR points in three outings, including two touchdowns. With a favorable matchup against the Chargers
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