Week 15 DraftKings DFS Strategy Overview (Main Slate)

Expert Picks by Adam as of December 14, 2025!

It’s Sunday morning, December 14, 2025, and Week 15 brings a massive 13-game DraftKings DFS main slate! With bye weeks behind us, raw points are critical, but roster stability is key as playoff-contending teams offer safer usage, while eliminated teams provide value through pricing inefficiencies. Let’s break down the strategy.

🔑 Quarterback Strategy

⭐ Top Spend-Up: Matthew Stafford

– Highest team total (30 points)
– Best game environment (54.5 O/U)
– Lions funnel production to QBs and WRs
– Elite stacking options: Puka Nacua / Davante Adams
Stafford is your primary tournament QB this week.

💰 Best Value: Marcus Mariota

– $5,000 salary opens everything
– Rushing floor + pass volume
– Giants allow top-5 QB fantasy points
– Ideal for CMC + Puka builds

🏃‍♂️ Running Back Breakdown

🔒 Core Play: Christian McCaffrey

– Highest usage RB in football
– Leads all RBs in targets & red-zone touches
– Titans defense is non-threatening
– Playable in all formats

💸 Best Value: Woody Marks

– 87% snap share last game
– 26 carries in relief role
– Cardinals allow 2nd-most RB FPPG recently
– Monitor practice, but elite salary-adjusted upside

Other RBs to Mix In:

– Jahmyr Gibbs (GPP pivot)
– Derrick Henry (touchdown equity)
– Kenneth Walker III (leverage)

📡 Wide Receiver Targets

🔥 WR1 Priority: Puka Nacua

– Nuclear ceiling
– Lions allow most WR FPPG
– Adams doesn’t hurt his volume
– Lock-button play if salary allows

💰 Best Value: Jakobi Meyers

– 28 targets in 4 weeks
– TDs in 3 straight games
– Jets defense collapsing
– Excellent mid-tier floor + ceiling

Other Strong Options:

– Jaxon Smith-Njigba
– Ja’Marr Chase
– Nico Collins
– Wan’Dale Robinson